Posts tagged with "Patients"

MIT: Liver transplant deaths reduced by 20%

Demand for liver transplants is much higher than organ supply, resulting in approximately 2,400 deaths every year. Also problematic is the current model used to identify and prioritize the “sickest” patients, which does not allow for equitable access to all waitlisted candidates, with a particular disadvantage to women. To address these issues, MIT Sloan School of Management Prof. Dimitris Bertsimas and Prof. Nikos Trichakis utilized machine learning to create a model that reduces mortality by 20%, averting nearly 400 deaths each year. Their model, Optimized Prediction of Mortality (OPOM), also provides a fairer and more equitable allocation to candidate groups, including women.

“There are many significant benefits to using this new model over the current system. Unlike the current system, which makes some arbitrary choices and results in bias against certain populations, OPOM’s methodology for prioritization is clear and understandable to surgeons — and it can save hundreds of additional lives every year,” says Bertsimas.

Trichakis noted, “OPOM fixes many of the current system’s problems because it was designed specifically for liver patients using real data. As a result, it can accurately prioritize patients across all populations without bias. This shows the potential of machine learning technology to help guide clinical practice and national policy on transplants.”

The researchers explain that the current model created in 2002 depends on the Model for End-Stage Liver Disease (MELD) score to rank disease severity and priority for receiving a liver transplant. As certain patient populations are at risk of death or of becoming too sick or unsuitable for transplantation based upon disease progressions that are not captured in their MELD score, the system arbitrarily grants them “exception” points. While the overall MELD score has led to a more objective ranking of candidates awaiting liver transplantation, the process of MELD exception point granting has resulted in inequitable and undesirable outcomes.

More specifically, the MELD exception points policy has disadvantaged women. “Data shows that women have historically had less access to liver transplantation and have had higher death rates on the wait list,” notes Trichakis. “This is due to the awarding of exception points to cancer patients, as more than 75% of those patients are men. Women also tend to have lower muscle mass and higher sodium levels, which lowers their MELD scores.”

Using a state-of-the-art machine learning method developed at the MIT Operations Research Center and real historical data from liver patients, the researchers sought a better way to prioritize the allocation of organs. With OPOM, they asked the question: What is the probability that a patient will either die or become unsuitable for liver transplantation within three months, given his or her individual characteristics?

They found that the OPOM allocation outperformed the MELD-based prediction method in terms of accuracy and fairness. In simulations, OPOM averted significantly more waitlist deaths and removed the bias against women. As a result, it allowed for more equitable and efficient allocation of liver transplants.

“Unlike MELD, which relies on an inexact approach of exception point assignment, OPOM allows for accurate prioritization of all candidates and removes bias for or against particular groups,” says Trichakis.

Bertsimas adds, “If we use this model to change how we measure mortality and allocate livers, the death rate will decrease by 20%, which is very significant. We’re hopeful that our findings will affect the national policy.”

Bertsimas and Trichakis are coauthors of “Development and validation of an Optimized Prediction of Mortality (OPOM) for candidates awaiting liver transplantation” with transplant surgeons Dr. Ryutaro Hirose of the University of California and Dr. Parsia A. Vagefi of the University of Southwestern Medical Center. Additional coauthors include MIT Sloan students Yuchen Wang and Jerry Kung. Their paper has appeared online in the American Journal for Transplantation.

Starlight Xperience for Children

Starlight Children’s Foundation, an organization whose mission is to create moments of joy and comfort for hospitalized kids and their families, unveiled today its newest initiative, Starlight XperienceTM virtual reality, a groundbreaking new technology program that offers millions of seriously ill children a fun and exciting way to explore the world and beyond through the magic of VR.

To watch a video on Starlight Xperience and how it helps kids, please see here.

Built for the Lenovo Mirage Solo with Daydream, Starlight Xperience features a state-of-the-art and hospital-ready headset that comes preloaded with age-appropriate and dynamic content geared toward entertainment and distraction for hospitalized kids, which has been specifically modified to meet strict infection safety protocols for use in hospital settings. Pre-loaded content includes educational field trips to exotic locations through Google Expeditions and Street View, fun interactive stories like Star Wars: Droid Repair Bay by ILMxLAB, and Lola and the Giant, popular apps such as Ocean Rift and Hello Mars, and meditation exercises and therapeutic games such as Relax VR, which allows the patient to escape into beautiful environments.

Starlight Xperience was created in collaboration with Founding Sponsor, Star Wars: Force for Change, the charitable initiative from Lucasfilm and The Walt Disney Company that harnesses the power of Star Wars to empower and improve the lives of children around the world. Through grant funding provided by The Walt Disney Company and Niagara Cares – the philanthropic arm of Niagara Bottling – as well as charitable donations from grassroots donors, Starlight Xperience will be provided at no cost to Starlight’s network of more than 800 children’s hospitals and other health care facilities across the US.

“We believe Starlight Xperience has the potential to transform the hospital experience for millions of seriously ill children and their families,” said Chris Helfrich, CEO of Starlight Children’s Foundation. “We’re thrilled to stand beside The Walt Disney Company, Google, Lenovo and Niagara Cares in unveiling this exciting new program, which is the latest evolution in our 35-year history of bringing innovative entertainment technologies to hospitalized kids.”

“Providing these unique entertainment experiences reflects our commitment to bring comfort during what can be difficult times for kids and families. This is part of our Disney Team of Heroes initiative, which includes a $100 million commitment to children’s hospitals,” said Elissa Margolis, senior vice president, Enterprise Social Responsibility for The Walt Disney Company. “The collaboration with Google and Lenovo is the perfect blend of technology and content that we’ll be able to deliver to kids during their hospital stay.”

“Our goal has always been to create virtual reality experiences that are accessible, useful, and relevant to as many people as possible,” said Amit Singh, VP of Business & Operations for AR & VR at Google. “Starlight Xperience is a shining example of that goal coming to life in a really great way. We’re thrilled to be able to support Starlight in bringing transporting VR experiences to hospitalized children across the country.”

“We are thrilled to be working with Starlight and Google to bring technology to hospitalized children in their time of need. Helping to provide a solution for the children and their families allows us to truly make a difference for the better,” said Gunjan Shah, general manager for North America Smart Devices at Lenovo.

Starlight Xperience was developed in part through a series of grants provided by Starlight to the CHARIOT program (short for Childhood Anxiety Reduction through Innovation and Technology) at Lucile Packard Children’s Hospital Stanford. CHARIOT implements new technologies in the hospital that are nontraditional yet familiar to children to engage and distract them during stressful or painful procedures, keeping clinical usage in mind and improving upon the typical hospital experience. This past summer, Starlight Xperience was soft launched and tested at five children’s hospitals: Lucile Packard Children’s Hospital Stanford, Children’s Hospital Colorado, Cincinnati Children’s Hospital Medical Center, Gillette Children’s Specialty Healthcare in St. Paul, Minn., and Texas Children’s Hospital.

“At Gillette Children’s Specialty Healthcare, virtual reality has been a fantastic addition for our patients,” said Chantel Barney, Ph.D., a clinical scientist who leads Gillette’s VR program. “In some instances, we’ve been able to curb the anxiety and fears our kids typically experience during procedures such as blood draws, transfusions, wound cleanings, casting and more. It’s a wonderful distraction for kids and parents alike.”

“We’re proud to support Starlight Xperience and look forward to bringing smiles to the faces of hospitalized children through this educational and inspirational program,” said Andrew Peykoff II, President and CEO, Niagara Bottling. “This technology makes learning fun and we’re excited to expand the program to even more children.”

Thanks to the grants provided by The Walt Disney Company and Niagara Cares, in addition to the generosity of charitable donations from individuals, Starlight is on track to deliver up to 1,000 Starlight Xperience kits to its network of hospital partners by the end of 2018, with a goal of doubling that by the end of 2019. A donation to Starlight will entertain, educate and inspire hospitalized kids across the US through stimulating immersive experiences that transport children from the hospital to any place in the world – or beyond – through the magic of virtual reality.

The public is invited to learn more and support the program online at www.starlight.org/starlight-xperience.

ABOUT STARLIGHT CHILDREN’S FOUNDATION
Starlight creates moments of joy and comfort for hospitalized kids and their families. For 35 years, Starlight’s programs have positively impacted more than 60 million critically, chronically and terminally ill or injured children in the US, Canada, Australia and the UK. With your help, more kids and their families will enjoy Starlight Gowns, Starlight Fun Centers and other Starlight programs at a children’s hospital or facility near you. Support Starlight’s work by visiting www.starlight.org and by following Starlight on Facebook, Instagram and Twitter.

ABOUT STAR WARS: FORCE FOR CHANGE
Star Wars: Force for Change, a charitable initiative from Lucasfilm and Disney, harnesses the strength of Star Wars to empower and improve the lives of children around the world. Since 2014, it was inspired by Star Wars fans, and the countless hours they have dedicated to philanthropy over the past four decades. To date, over $16 million has been raised for charitable causes around the world on behalf of Star Wars: Force for Change. With a bright future ahead, and new Star Wars stories to be told, Force for Change aims to continue collaborating with causes and encouraging others to be forces for change in their own community. To learn more, please visit ForceForChange.com.

ABOUT THE WALT DISNEY COMPANY
The Walt Disney Company, together with its subsidiaries, is a diversified worldwide entertainment company with operations in four business segments: Media Networks; Studio Entertainment; Parks, Experiences and Consumer Products; and Direct-to-Consumer and International. Disney is a Dow 30 company and had annual revenues of $55.1 billion in its Fiscal Year 2017.

ABOUT LENOVO
Lenovo (HKSE: 992) (ADR: LNVGY) is a US$45 billion Fortune Global 500 company and a global technology leader in driving Intelligent Transformation through smart devices and infrastructure that create the best user experience. Lenovo manufactures one of the world’s widest portfolios of connected products, including smartphones, tablets, PCs (ThinkPad, Yoga, Lenovo Legion), data centers and workstations as well as AR/VR devices and smart home/office solutions. Lenovo works to inspire the difference in everyone and build a smarter future where everyone thrives. Follow us on LinkedIn, Facebook, Twitter, Instagram, Weibo, read about the latest news via our Storyhub, or visit our website at http://www.lenovo.com/.

ABOUT NIAGARA CARES
Niagara Cares, a philanthropic arm of Niagara Bottling, is committed to supporting local and national community initiatives serving children and families in need by engaging stakeholders and investing its resources. Niagara Cares efforts include national strategic partnerships, local community grants, employee engagement, volunteerism and the Andrew D. Peykoff, Sr. Scholarship Program. For more information, visit www.niagarawater.com/niagara-cares.

New AI app reduces back pain by 40%

Boston based digital therapy startup Kaia Health launches a new app that uses AI and patent pending motion tracking technologyto personalize treatment programs tomanage and treat chronic low back pain(LBP) which has been shown in clinical studies to reduce chronic back pain by 40% and could save the US economy billions each year.

Created by Kaia Health the motion tracking technology requires no additional hardware.The app has been registered as a Class 1 medical device with the FDA which allowsusers to self-manage their back pain through physical exercise, behavioural exercise (e.g. relaxation and meditation) and education.

Earlier this year the digital therapy startup launched the Perfect Squat Challenge App, the world’s first Artificial Intelligence-powered motion tracking fitness app that turns a smartphone into a personal trainer. In Q4 2018 the company intends to roll out20 more motion tracking exercises for the app.

According to the World Health Organization (WHO) LBP is the single leading cause of disability worldwide. In fact, according to the American Chiropractic Association(ACA) 31 million Americans experience LBP,and one half of all working Americans admit to having back pain symptoms each year.

The epidemic of prescription opioid overuse and abuse has also led many health groupsincluding the ACA, the American College of Physicians (ACP) and the American Association of Pain Management (AAPM) to reconsider the value of a non-pharmalogicalapproach to common conditions such asLBP.

The ACP, the largest medical specialty society in the world, updated its LBPtreatment guidelines in 2017 to support a conservative approach to care. Published in the Annals of Internal Medicine, and based on a review of randomized controlled trials and observational studies, the ACPguidelines cite heat therapy, massage, acupuncture and spinal manipulation (a centerpiece of chiropractic care) as possible options for non-invasive, non-drug therapies for LBP. The guidelines state that only when such treatments provide little or no relief should patients move on to medicines such as ibuprofen or muscle relaxants, which research indicates have limited pain relief effects. According to the ACP, prescription opioids should be a last resort for those suffering from LBP, as the risk of addiction and overdose may outweigh the benefits.

The Kaia app has been developed by aleading digital therapy company Kaia Health in conjunction with physiotherapists, pain management physicians and clinical psychologists.

The app uses a multidisciplinary digital approach which offers users online video-based learning programmes that covereducation, physiotherapy (includingexercises for the lower back and lateral muscles) and psychological strategies(including mindfulness and muscle relaxation).

The AI tailors treatment programs for each user from over 120 exercises, and motion tracking technology ensures that the exercises are performed correctly using a smartphone, tablet or iPad without the need for additional hardware.

Each session lasts for 15 minutes and can be accessed anywhere 24 hours a day. The app also features a chat function whichconnects users to a physiotherapist or sport scientist for motivation and exercise related questions.

Two clinical trials into the Kaia app show a significant reduction in LBP by 40%, well above the clinical threshold of pain improvement. The second study shows a40% long-term retention of users for aminimum of 6 months.

The Kaia app was developed in Germanywhere it has been downloaded over 100,000 times in its first year. The Kaia app is now being reimbursed for over 20 million patients globally.

Kaia Health is member of the Digital Therapeutics Alliance (DTA), an association of international manufacturers for digital therapeutic products that are evidence-based.

Konstantin Mehl, CEO of Kaia Health says:Opioid addiction and overdose is a huge issue in the US, and is, according to the ACP, a last resort for those suffering from LBP. Their 2017 LBP treatment guidelines support a non-pharmalogical approach to care using non-invasive, non-drug therapies. A holistic, multidisciplinary treatment of LBPhas always been a resource-intense, costlyundertaking which makes it hard forpatients to get access to the therapy.However, with the Kaia app we’re digitising therapy which offers as many patients as possible access to effective treatment ofLBP. This empowers and motivatesindividuals to take control, and self-manage their condition with evidenced-based, non-pharmacological, cost-effective alternatives and this could save the US economy billions each year. The Kaia app, and advances in technology, demonstrates why we need to rethink how we treat diseaseconditions such as LBP, and make digitalself-management a more realistic part of treatment.

The Kaia app is available on iOS and Android, and can be downloaded via GooglePlay and AppStore. The first 7 days of the program are free. To unlock the full functionality the costs are: 3 months: $23.99, 6 months: $64.99 and 12 months: $94.99.

About Kaia Health www.kaia-health.com
Founded in 2016, Kaia Health is a leading digital therapy company that creates evidence-based treatments for a range of disorders including back pain, Parkinson’s disease, osteoarthritis and chronic obstructive pulmonary disease. Kaia Health uses innovative technology including artificial intelligence and apps, and works with experts in each medical field to create an interdisciplinary digital approach. This empowers and motivates individuals to take control and self-manage their condition with effective, non-pharmacological, digital alternatives at low costs.

H&M Donates $200,000

NEW YORK, June 12, 2018/PRNewswire/ -In honor of the reopening of its location at The Mall of San Juan, H&M is proud to make a $200,000 donation to San Jorge Children’s Foundation.

In anticipation of the June 7th reopening of its location at The Mall of San Juan, in San Juan, Puerto Rico, H&M supported the local community through San Jorge Children’s Foundation. H&M first partnered with nonprofit GLAM4GOOD and donated over 2,000 articles of clothing for a free pop up shop held at San Jorge Children’s Hospital on May 23rd for patients and their families, as well as doctors and nurses of the hospital. Building upon this initial outreach, sale proceeds from both Puerto Rican H&M locations during June 7th -10thwere donated to San Jorge Children’s Foundation, amounting to a donation of $200,000.

“We are so thrilled to help the local community in Puerto Ricowith this donation to San Jorge Children’s Foundation,” said Daniel Kulle, North American President of H&M. “We are also happy to be reopening our first location on the island for our customers and employees.”

H&M opened its first location in Puerto Rico at The Mall of San Juan on June 9th, 2016 and its second location at Plaza del Sol in Bayamón on September 1st of the same year. The company currently employs approximately 50 people on the island of Puerto Rico and is proud to support the local community.

The GLAM4GOOD Foundation is a non-profit organization that creates and celebrates social impact and empowerment through beauty and style. The foundation partners with non-profits, media outlets and fashion and beauty brands to provide life-changing makeovers, clothing giveaways and confidence-bolstering fashion and beauty initiatives for everyday heroes and people in need.

San Jorge Children’s Foundation is a nonprofit organization dedicated to the health and welfare of children in Puerto Ricowith the aim to help improve patient’s quality of life. The foundation is committed to providing services for families in need and has a network of more than 1500 active patients.

For more information on GLAM4GOOD:
https://glam4good.com/
@glam4good

For more information on San Jorge Children’s Foundation:
http://www.fundacionsanjorge.org/

For more images of the opening:
http://assignments.gettyimages.com/mm/nicePath/gyipa_public?nav=pr586972265

About The Mall of San Juanlocation:
H&M, Hennes & Mauritz (H&M) at The Mall of San Juan is located at 1000 The Mall of San Juan Blvd, San Juan, PR 00924. The store can be reached by phone at (855) 466-7467. Store hours will be Monday through Thursday 10:00 a.m. – 7:00 p.m., Friday and Saturday 10:00 a.m. – 9:00 a.m. and Sunday 11:00 a.m.– 7:00 p.m.

H & M Hennes & Mauritz AB (publ) was founded in Sweden in 1947 and is quoted on Nasdaq Stockholm. H&M’s business idea is to offer fashion and quality at the best price in a sustainable way. In addition to H&M, the group includes the brands COS, Monki, Weekday, Cheap Monday, & Other Stories and H&M Home as well as ARKET. The H&M group has 47 online markets and more than 4,700 stores in 69 markets including franchise markets. In 2017, sales including VAT were SEK 232 billion. The number of employees amounts to more than 171,000. For further information, visit about.hm.com.

SOURCE H&M

Web Site: http://hm.com

Clinic of Kohll’s

Preventative Medical Clinic of Kohll’s Pharmacy … Non-Surgical Beauty is on the Rise for Patients on the Go!

Study: On average, women spend more than $313 a month on their appearance. For millions of Americans, it’s not just products, but procedures keeping them looking good.”It’s addicting. You start with Botox, you want a little more you realize how fast and easy it is” said Bobbie Vetock, clinic director at Preventative Medical Clinic of Kohll’s Pharmacy and HomeCare.

Treatments like Botox helped to boost business at the clinic off 114th & Dodge. Vetock says sales have doubled in the past two years.According to a study done by One Poll for Groupon, the average woman spends about $313 a month on her appearance.That adds up to $3,756 a year, and more than $225,300 over a lifetime.​Vetock tells me the most popular procedure at her office is Botox because of the quick results and minimal amount of time spent on the procedure.”People are coming on their lunch breaks, scheduling appointments over lunch. You can be in and out of here in 15-45 minutes, and look different,” said Vetock.

Another popular service available at Preventative Medical Clinic of Kohll’s Pharamacy: Many of us can point to any part of our body to find some unwanted fat. And for those who have extra fat on their chin, you’re in luck. Preventative Medical Clinic of Kohll’s are using treatments, such as Kybella, to tighten the chin area. Preventative Medical Clinic of Kohll’s Pharmacy was one of the first in the Nebraska to offer Kybella, a drug that helps to dissolve fat below the jawline in order to minimize the appearance of a double chin.​”It really revolutionized the treatment for saggy chin, or chin that has unwanted fat” said Justin Kohll V.P.  Patients don’t go under the knife. Kybella is injected into the chin area to get rid of the unwanted fat.​​

SculpSure is another popular procedure drawing patients to clinics around the Omaha metro area,It’s a non-surgical fat-reduction treatment that uses controlled cooling to eliminate stubborn fat that resists all efforts through diet and exercise.

Heartland Institute Experts React to FDA

The advisory panel to the Food and Drug Administration voted 5-to-4 to reject a claim from Philip Morris International Inc. that “Switching completely to IQOS presents less risk of harm than continuing to smoke cigarettes.” Phillip Morris claims that using their IQOS device, which heats tobacco rather than burn it, could reduce the risk of tobacco related health issues compared to cigarettes.

“How many more smokers will have to die on the FDA’s watch until they catch up to the rest of the world when it comes to supporting harm reduction technologies?” Director of Government Relations John Nothdurft said. “The rest of  the world is far ahead of the United States in terms of supporting policies that help smokers quit or at a minimum move to less harmful alternatives such as heat-not-burn products, e-cigarettes, and snus.”