Posts tagged with "Los Angeles"

We All Shine EP Tracklist

YNW Melly latest project, WE ALL SHINE features Kanye West and Fredo Bang, the project is due out this Friday, January 18, 2019.
Melly is the exciting Florida rapper, who captivated music lovers everywhere with his massive single, “Murder On My Mind” and popular documentary, MELLY. YNW Melly’s critically-acclaimed EP, I Am You, dropped in September of 2018. Less than a year into music, the 19 year-old has accumulated over 165 million views on YouTube. Stands out tracks such as: “Murder On My Mind,” “Virtual,” and “Melly the Menace” has shot Melly to the forefront of Florida rap and caught the attention of The Fader, Forbes, Pitchfork, Complex, Genius, Hypebeast, Hot New Hip-Hop, Elevator, and many more.
WE ALL SHINE will be available on all streaming platforms Friday, January 18th.
TRACKLIST – WE ALL SHINE:
1. City Girls
2. No Heart (Love No More)
3. Rolling Loud
4. Robbery
5. Beat A N*gga Block
6. Hold Up (Wait 1 Min)
7. No More
8. No Holidays
9. Mixed Personalities Ft. Kanye West
10. Why You Gotta Walk Like That???
11. F*ck PNC Bank
12. Ingridientz Ft. Fredo Bang
13. Curtains (Burtains)
14. Control Me
15. Alarm
Bonus Track: Butter Pecan
DOCUMENTARY – MELLYhttps://youtu.be/TGIp4H_JvZg
EP – I Am YouTidal Spotify Apple Music | YouTube Soundcloud
MUSIC VIDEO – Murder On My Mindhttps://youtu.be/hqDinxaPUK4
MUSIC VIDEO – Freddy Krueger: https://youtu.be/FWC9pBfrUwg

YNW Melly Announces New Project & Tour

YNW Melly is the exciting Florida rapper, who captivated music lovers everywhere with his massive single, “Murder On My Mind.” After releasing his popular documentary, MELLY, the Gifford native is now announcing his newest project, WE ALL SHINE, due out January 18th. Starting the year off strong, Melly hits the road for his first headlining tour,WE ALL SHINE TOUR January 27th, which begins in Atlanta, GA.
YNW Melly’s critically-acclaimed EP, I Am You, which dropped in September of 2018. The juxtaposition of misery stricken lyrics and beautifully exuberant production has YNW Melly delivering a remarkable body of work to both loyal fans and curious music lovers around the world. Less than a year into music, the 19 year-old has accumulated over 165 million views on YouTube. Stands out tracks such as: “Murder On My Mind,” “Virtual,” and “Melly the Menace” has shot Melly to the forefront of Florida rap and caught the attention of The Fader, Forbes, Pitchfork, Complex, Genius, Hypebeast, Hot New Hip-Hop, Elevator, and many more.
The attention on Melly transcends music. He’s uniquely fashion-forward and delivers the most compelling visuals to bring his words to life. When talking to The Fader, Melly said “When you into fashion and dressing, people are gonna judge you and try to test you.” At only 19 years old, and having been in and out of jail – Melly isn’t concerned with people’s assumptions. Given the opportunity to make waves in music, he’s living in the present and laboring beautiful rap ballads.
Tickets for the WE ALL SHINE TOUR are available now. Be sure to keep a look out for Melly’s next project, WE ALL SHINE January 18th.

Mob Museum Debuts Tech at the Museum

The Mob Museum, The National Museum of Organized Crime and Law Enforcement located in downtown Las Vegas, this year launched “Organized Crime Today,” a technology-driven exhibition dedicated to present-day topics. Featuring artifacts as well as fully interactive, 17-foot-long touch screen wall, the exhibition enables Museum guests to take a deep dive into the Global Networks of organized crime operating around the world in the 21st century. This elaborate exhibition launched in February of 2018, along with three other brand-new permanent exhibitions the award-winning, American Alliance of Museums-accredited institution debuted this year.

While most of the Museum covers the intriguing history of organized crime and its battle with law enforcement through decades, Organized Crime Today addresses contemporary iterations of this illegal activity. The Global Networks touchscreen wall elaborates on contemporary crime rackets—illegal enterprises that span the globe and profit off everything from drug and human trafficking to product counterfeiting, money laundering and cybercrime. The exhibit addresses the most prominent organized crime groups active in the world today and explores the complexities of organized crime with up-to-the-minute developments pulled from the day’s headlines.

For example, a recent addition to the Global Networks interactive wall spotlights the wildlife smuggling trade in Cambodia, where customs officials recently confiscated 3.5 tons of African elephant ivory—the largest cache of the smuggled contraband ever found in the country. Smugglers have been using Cambodia as a transit hub to feed the demand for ivory in China—which banned ivory sales in 2018—and Vietnam, where it is used in carved artwork, chopsticks and jewelry.

In addition, the screen offers the ability for experts around the world to videoconference into the Museum remotely and offer their analysis and insights into organized crime around the world. These programs are included in the price of general admission and offer Museum visitors the opportunity not only to hear from these experts, but also the chance to ask questions.

Museum visitors encounter other technology-enabled, interactive experiences as well. A Use of Force Training experience uses airsoft versions of police-style handguns and responsive video scenarios to demonstrate the training law enforcement officers receive regarding the use of deadly force. Meanwhile, in the Museum’s Crime Lab, visitors can learn about cause of death investigation with the assistance of life-sized, digitally generated subjects viewed on an interactive, touch-screen “autopsy table.”

Media attending CES 2019 who wish to visit the Museum should send their request tochristina@thevoxagency.com. For more information about the Museum and its Organized Crime Today – Global Networks exhibition, click here.

Swatch Launches Valentine’s Special

Valentine’s Day is within reach and so is Swatch’s TRIPLE LOVE! At long last, there’s a clear way to light up February 14th with zesty romance.

Does (s)he or doesn’t (s)he? What’s for sure is that there is TRIPLE LOVE on the wrist. This beauty features three transparent printed hearts in shades of red and pink, visible through a clear transparent dial and finished with a semi-transparent patterned bracelet. Delicately wrapped in distinctive heart- covered packaging, this limited and numbered edition of 5.143 pieces is a rare gift for that special someone. If only true love were this transparent!

2019 GOLDEN GLOBE NOMINEE LOUNGE

Secret Room Events presented a Hawaiian Style Retreat in honor of the Nominees for the 2019 Golden Globes . This luxury celebrity gift suite will took place at InterContinental Century City on Friday, Jan. 4th, 2019.

Open to only celebrities and media, this event hosted some of today’s most unique, fashionable and luxurious companies, products and services. From trips, to Hawaii. American Luxury Tours will be gifting 7 night stays to the Nominees and special media & Estancia La Jolla Hotel & Spa gifted a 2 night stay including breakfast and massages, high end jewelry, to hip and trendy baby and pet products and luxurious skin and hair care products, the Secret Room is a total pampering experience.

Secret Room Events sponsored this year’s event with Anne Neilson Home, Thomas George Estates, BARE NATURE.

Guests lucky enough to score an invite to experience this lavish event, The Secret Room Event, were provided luxurious services ranging from massages, Eye Lashes, Teeth whitening, Botox, fillers & nails. Also on hand Beverly Hills Tennis Academy will be giving free tennis gift certificates to the Nominees and media .

The following sponsors were on hand to gift their amazing brands:

Camouflage cellulite body Liner
Baroque & Rose
Greek Island Labs
Nuvelon
Anne Neilson Home
Relaxium
Buckle me baby car seat coats
Shore Bags
Sun Soaker Flexible solar
Dandy Blend
Silver Stork (care packages)
COPPER+CRANE™
HEATHERCHAPPLAIN.COM
BARE NATURE
Frill Plant –based frozen Dessert
Thomas George Estates
LELO
WET
Secret Celebrity Licensing ,LLC
Nicole Kelly , MD
A20 WATER/ Think Alkaline

Nominees and special media walked out with a huge tote bag filled with our amazing gift bags sponsors:

Estancia La Jolla Hotel & Spa
American Luxury Tours
Elyptol Inc
San Clemente Cookie Dough Co
RX BAR
LIVIE AND LUCA
Mahifinefoods.com
LIFE CHOICE LTD
OUR PLANET SOAP
Delia organics
Bae Vegan perfume
Charlston & Harlow candle Co
Nancy Ganz
H2rOse
Cherry Blooms cosmetics
Cover Made Bedding
Chefs cut real jerky
Pacha soap Co
Jane Bakes cookies
LUMIFY™ redness reliever eye drops
Nail-snail.com
Dr Gingers Healthcare products LLC
LIVE LOVE POP
Celsius
Boho By Moe
Popcorn ,Indiana
Punch gunk
Dalmatia Imported by Atalanta
Thorlo
Bubbies Ice cream

WINNERS:

Patricia Arquette, 360 magazine, golden globes, jc olivera

Patricia Arquette (shot by JC Olivera)

Linda Cardellini, 360 magazine, golden globes, jc olivera

Linda Cardellini (shot by JC Olivera)

FREDERICKSBURG

By Alexandria Baiz × Vaughn Lowery

Fredericksburg, Texas the destination of historical sites and culture welcomes us. With the hidden treasures of food, wine and goods the Texas Hill Country is a must-visit.

Beginning with a stay at the one and only Hanger Hotel. This hotel has a WWII hangar of the romantic 1940’s to it’s design with fine woods and custom carpets. Famous for the Observation Deck on the second floor with views adjacent to the airport to see the planes come and go from one end of the runway to the end.

Later a stop to the Pioneer Museum Complex preserved from the 19th century German Pioneer days. In the mid-1840s Germans faced every obstacle to come to Texas and create a unique German colony in the heart of the Texas Hill Country. The Museum strives to preserve and tell this story. With a combination museum and historical site, it reaches over 3.5 acres on Main Street in downtown Fredericksburg.

Dinner at Das Peach Haus that houses delicious jams, jellies and sauces made by Fischer and Wieser Speciality Foods. The Historic roadside fruit stand offers gourmet products with unique flavor combinations. The Tasting Room offers tastings from two Texas wineries, which change out every two months. Vintage wines are paired with international assortment of cured meats and cheeses. Fischer and Wieser include more than 70-award-winning products, which each inspire culinary adventures around the world by being able to purchase online.

Clear River Pecan does things differently with hot-from-the-oven baked goods, homemade ice cream and house deli. Homemade ice cream with high-quality ingredients has been voted as the third best ice cream in Texas. For a bite to eat the deli and salad selection is notable with house favorites like the Chipotle Ranch Chicken Wrap. Fresh baked goods can satisfy any sweet tooth with an Apple Strudel, Peach Cobbler and everything in between.

Tour at the George H.W. Bush Gallery at The National Museum of the Pacific War dedicated exclusively to telling the story of the Pacific Theater in World War II. The Museum is noted for its historic materials with iconic elements of the Pacific War era. Guided tours debut the newly renovated Pacific Combat Zone, a realistic environment for a deep understanding of the momentous struggle between Allied Forces and Japanese forces.

For lunch we enjoy an Arts District Stroll through the Peach Tree Gift Gallery and Tea Room. With the Cottage style restaurant, you will find a combination of fresh, homemade breads, soups, salads, sandwiches and desserts. For over 39 years this family owned business has been a destination in Fredericksburg, because of the seasonal fruits and vegetables they use.

After lunch, we took an art tour through the streets of Fredericksburg to meet with the area’s top galleries. Insight Gallery represents the cities artists and sculptors that today work on landscape, figurative, impressionistic, still life, wildlife and western art. The Good ART Company is beautiful with a contemporary fusion in a restored 4,000+ square foot historical building with high ceilings and limestone walls. The gallery features an array of genres with some of the best regional, national, and international artists. Koch Gallery owned and operated by Bert E. Koch a trader/broker for traditional, contemporary and modern Native American Art. For over 30 years it continues its long tradition of providing important works of art from all major cultural regions in North America. Artisans Gallery makes your artistic dreams reality with unique pieces that come in every medium, size and price range. RS Hanna a jewel for fine arts with original works of acclaimed artists. Workings range from oil, watercolor, bronze and wood. Gallery 330 is the newest addition to the art scene representing contemporary established artists whose works include sculpture, painting and prints, serigraphs and watercolors.

The Holiday Wine Trail takes us to Texas’s countryside to travel along Wine Road 290 with visit to award winning wineries.

The trail begins at Stout’s Trattoria at Grape Creek Vineyards a 100-acre vineyard estate. With oaks and vines surrounding the tasting rooms there is a romantic Tuscan setting that is truly unforgettable. The Vineyards have won over 100 medals in the last two years for their wines.

In the heart of the Texas Hill Country, 4.0 Cellars offers a relaxing and elegant setting to discover the infamous Texas Wines. In a private tasting room we enjoy a wine and chocolate pairing. With four award-winning chocolate truffles from local chocolatier with four carefully selected dry red wines.

Dinner at August E’s, known for it’s organic produce and superb local suppliers. August E inspired by his Thai roots and years in various culinary pursuits throughout the world has created a Nouveau Texas Cuisine. Utilizing ingredients like: Niman ranch Natural Premium Aged Angus steaks and local farmers fruits and vegetables year round. Menu specials change seasonally based on the creative mood of Chef Leu like duck from Maple Leaf Farms and Sashimi Grade Fish.

A favorite in the Texas Hill, we enjoy dinner at Otto’s German Bistro. Menu changes weekly with the season so each visit is an exciting adventure. Dedicated to local, organic produce ingredients that are always fresh and the highest quality.

We enjoy breakfast at Java Ranch a locally owned coffee stop. The ranch serves the finest hot or iced coffee drinks anywhere including lattes, cappuccinos, Hill Country roasted brewed coffee, Americanos and mochas. To start the day off we dive in a breakfast taco or kolaches, house favorites.

We take a visit to the Lyndon B. Johnson National Historical Park for a “Texas style” morning. During his administration, Johnson signed more education bills into law than any other president. In respect to that we see his first school where he signed the landmark Elementary and Secondary Education act of 1965. Other stops include the family cemetery and the LBJ Ranch Show.

In the afternoon we endow in lunch and a beer tasting at Altstadt Brewery Fredericksburg’s newest brewery an authentic Bavarian brewery. Dedicated to creating the purest drinking beers the 120-acre old world destination features a fine dining restaurant, brewery tours and a beautiful venue. Brewery exclusives include traditional brews like Schwarzbier, a traditional German “Black Beer.”

With over 150 specialty shops, shopping is one of the primary reasons visitors come to Fredericksburg. In store we see everything from clothing, upscale home accessories, to unique collectibles and more perfect items for holiday shopping. Blackchalk Home and Laundry originally an old laundromat had been transformed into an electric home goods store. The hip store features gifts, kitchen goods, and one of a kind rugs. The infamous Christmas Store open year round specializes in collectibles. For collectors, this store is paradise with Department 56 miniature villages and Christopher Radko blown glass ornaments. The Hill Country Outfitters and The Grasshopper offer products to fit the hill country lifestyle in downtown Fredericksburg. Brands like Ugg and The North Face are housed in the Outfitters. The Narrow Path Tasting Room inside is an intimate space with French cafe feelings in the air.

To continue the Holiday Wine Trail, a stop at Signor Vineyard in the rolling hills of Central Texas. Where the Pedernales River meets Grape Creek, established by a friendship spanning three generations of two Texas families. Their focus is growing premium varietal fruit with soulful wines reflective of the unique terroir.

Our stay is perfect timing for the Fredericksburg’s 61st Annual Holiday Home Tour. A self guided tour showcasing unique local homes decorated in their holiday finest. With more than 22 vendors each year selling personal gifts, homemade foods and holiday items.

For dinner we dine at Navajo Grill, which encompasses an unusual blend of Hill Country craftsman design. Enjoying Southern cuisine composed with old and New Mexican flavors with a touch of Creole & Caribbean influences. Specialties like the Sunday Chicken Fried Steak dinner are served with housemade sauces and dressings.

After dinner drinks at Elk Store Winery & Distillery. Since 1895 the business has carried a family tradition that pays homage to the spirit of realizing the American Dream. In the footsteps of their great grandfather Todd Smajstrla along with Scott Hladky, produced moonshine, gin, rum, and whiskey. Since then, the business serves Incredible wines from all over the world. Along with small batches of handmade liquors by the bottle or cocktails.

Dinner at Rathskeller a full-service breakfast, lunch and dinner spot in downtown Fredericksburg. The menu selection is extremely versatile featuring German dishes and daily specials. On Friday and Saturday nights enjoy live music that house the restaurant.

Nothing better than the taste of handmade tortillas for breakfast at Hilda’s Tortillas. Hilda’s is a small family owned and operated business. Specializing in authentic Mexican fare their breakfast tacos and burritos are a must try. Twice a week 300 or more pounds of tortilla chips are produced within the restaurant.

For some fresh air we bike the quiet country backroads with Jack and Adams Bicycles. At Jack and Adams you can rent out Road, Tri-bike, Cruisers and even kid bicycles and accessories from a variety of brands. The Hill Country scenes with its rolling hills and panoramic views, is considered the cycling capital of Texas.

In addition to the speciality shops we visited above there is a collection of shops specializing in different festive treats. Emma + Ollie bakeshop takes classic treats we grew up loving and elevated them. The shop prides themselves on using only fresh ingredients; no processed foods, no artificial sweeteners, just pure dessert. The founders Emma and Ollie wanted the shop to feel as if customers stepped into an upscaled version of their own grandma’s kitchen. Chocolat store creator, Lecia Duke, was the first to introduce European-Style, liquid centered chocolate in the U.S. The truffle chocolates are of course a house favorite as the delicate shell gives way to the pure liquid flavor casades in your mouth. In addition there is also colette’s, creams, silk fudges, nut clusters, barks, and caramels. Fredericksburg Pecan Company provides fine quality of pecan products grown in the Texas Hill Country. Owners are dedicated to providing excellent quality pecans available for online order at reasonable prices with the best customer service. Pecans are flavored and glossed in everything from pecan brittle to pecan coffee.

Rustlin Rob’s Texas Gourmet Food is not your ordinary gourmet food, not limited to people who cook but to “foodies” of all ages. The store is enjoyable because it caters to anyone who loves to eat. With over 350 gourmet foods we can sample from ranging from peanut butters, mustards, bread mixes, and some 5 Alarm hot sauces.

Fredericksburg Pie Company mission is to serve pie that is as good as, or better than your mothers or grandmothers made. In store pies are made from scratch and selections change daily with up to 20 kinds of pie. While here, we enjoy an option of coffee, milk, and more with our slice of pie and even a book selection. Sugar free pies are also available with a call in a day before.

Lunch at the Farm Haus Bistro in the Fredericksburg Herb Farm, with an American menu with French and Italian influences. Owners Dick and Rosemary Estenson take us on a tour of the B&B Cottages based upon the design of the early historic Fredericksburg “Sunday Houses. These houses are inspired by German settlers who built these small “city houses” to use on the weekends to buy provisions and attend Sunday church. We also visit the Nature Spa area dedicated to a truly unique relaxing experience.

Exploring Main Street is incredible when we can enjoy Eisban, an outdoor ice skating on real ice. Alongside Marketplace and the Christmas Pyramid. Afterwards a trip to Luckenbach, Texas made famous by Waylon Jennings’ and Willie Nelson’s 1976 classic country hit.

For our last destination Dinner and wine pairing at local Cabernet Grill Texas Wine Country Restaurant. Chef/Owner Ross Burtwell’s wish is to create a lasting impression of culinary craft where guest feel at home. Known for his speciality in preparing the freshest seafood, Certified Angus Beef, wild game and ranch fare. The wine selection is also superb with over 75 selections from around the State of Texas. Tripadvisor has ranked the restaurant Top 10 in the nation and we know why.

The good art company, gallery, art, Fredericksburg Texas,  360 MAGAZINE

August E's, 360 MAGAZINE,  Fredericksburg Texas

War museum, Fredericksburg Texas, 360 MAGAZINE,  Vaughn Lowery

Altstadt Brewery, Fredericksburg Texas, 360, 360 MAGAZINE, Vaughn Lowery

Chocolat, lecia Duke, 360 MAGAZINE, Fredericksburg, Vaughn Lowery

January Art Walk Must-Sees

The Downtown Art Walk returns on Thursday, January 10th in the galleries and artist studios of Downtown Los Angeles! Begin your evening at the Spring Arts Collective inside The Last Bookstore at 453 S. Spring St., from 6-9PM. Enter the bookstore at 5th at Spring, and walk up the stairs to the mezzanine. Our team will be on hand to distribute free collectible Gallery Guides (maps), and share information on what to see and do throughout the evening! For more info on January Art Walk programming, visit the FACEBOOK EVENT PAGE.

Interested in our January 10th guided Art Walk Gallery Tour? Grab tickets here while you still can!

Other dates also available

Art Walk Galleries

Roughly 30 local galleries and art spaces participate in the Downtown Los Angeles Art Walk on the 2nd Thursday of each month. To find out more about these, please visit www.downtownartwalk.org/galleries, and don’t forget to follow us on Facebook! Free Maps (Gallery Guides) are available at any of the participating spaces, or at The Spring Arts Collective at 453 S. Spring St., Los Angeles, 90013 (up on the mezzanine) from 6-9PM on Thursday, January 10th.

EVENTS

DAC GALLERY

Worldbuilding

431 S. Broadway, Los Angeles, 90013

January 10th |  5-8PM

 

Worldbuilding is a group exhibition at DAC Gallery curated by Sarah Julig that explores a range of modalities through artists’ use of ceramics, digital animation, and mixed media to convey complex personal mythologies. The exhibition explores the contrasts between ceramics and digital animation, both in processes and historic lineages, exploring how contemporary artists use these divergent mediums to search their own internal narratives. Worldbuilding is on view during the January 10th Art Walk from 5-8pm, and through February 2nd. | MORE

LITTLE TOKYO ART COMPLEX

Downtown Art Walk Open Studios

262 S. Los Angeles, Los Angeles, 90013

January 10th | 7-10PM

Each Art Walk, the Little Tokyo Art Complex, an arts community located at Los Angeles and 3rd, opens its doors to the public. Make your way through the studios of resident artists and discover original handmade art, including painting, printmaking, sculpture, and more. Additionally, LTAC offers changing exhibitions each month in their shared gallery space. For more information on the Little Tokyo Art Complex, please visit them on Facebook! | MORE

THE HIVE GALLERY & STUDIOS

Hive Tarot 10: A Decade of Tarot Shows from The Hive Gallery

729 S. Spring, Los Angeles, 90014

January 10th |  6-10PM

On the January 10th Downtown Art Walk, The Hive welcomes the new year with the launch of “Hive Tarot 10″, featuring original tarot card artwork by 22 Hive artists from 2018 for the soon to be printed HIVE TAROT 10 deck. Other themed exhibitions are also featured in the space, along with works by resident artists. “Hive Tarot 10” is on view during the January 10th Downtown Art Walk from 6-10pm, and through February 3rd. | MORE

DOWNTOWN INDEPENDENT THEATER

LA Story #1

251 S. Main, Los Angeles, 90012

January 10th |  6-10PM

Tickets $20 at the door 

On the January 10th Art Walk, The Independent Theater will be the site of LA Story # 1, featuring live variety–style musical performances produced and curated by local artist and creative director Gail Zone. Zone. Performances begin with a Video Art Gallery, featuring the premiere screening of “Botany of Desire” by Sean Yang, followed by “Sand & Snjor” by Fridgeir Trausti Helgason, and additional videos by Jason Ruscio, and J-Walt’s Lucid Dreamscapes. LA Story # 1 is comprised of musical performances in 3 acts, set in the Pueblo de Los Angeles. | MORE

Support

Did you know, the Downtown Art Walk does not receive funding from food truck and vendor lots? We rely on donors like you to keep this cultural event going strong! Please show your support for our community by making a donation at the following link: www.DowntownArtWalk.org/Donate

To become a sponsor of Art Walk, please contact us.

MIT: Liver transplant deaths reduced by 20%

Demand for liver transplants is much higher than organ supply, resulting in approximately 2,400 deaths every year. Also problematic is the current model used to identify and prioritize the “sickest” patients, which does not allow for equitable access to all waitlisted candidates, with a particular disadvantage to women. To address these issues, MIT Sloan School of Management Prof. Dimitris Bertsimas and Prof. Nikos Trichakis utilized machine learning to create a model that reduces mortality by 20%, averting nearly 400 deaths each year. Their model, Optimized Prediction of Mortality (OPOM), also provides a fairer and more equitable allocation to candidate groups, including women.

“There are many significant benefits to using this new model over the current system. Unlike the current system, which makes some arbitrary choices and results in bias against certain populations, OPOM’s methodology for prioritization is clear and understandable to surgeons — and it can save hundreds of additional lives every year,” says Bertsimas.

Trichakis noted, “OPOM fixes many of the current system’s problems because it was designed specifically for liver patients using real data. As a result, it can accurately prioritize patients across all populations without bias. This shows the potential of machine learning technology to help guide clinical practice and national policy on transplants.”

The researchers explain that the current model created in 2002 depends on the Model for End-Stage Liver Disease (MELD) score to rank disease severity and priority for receiving a liver transplant. As certain patient populations are at risk of death or of becoming too sick or unsuitable for transplantation based upon disease progressions that are not captured in their MELD score, the system arbitrarily grants them “exception” points. While the overall MELD score has led to a more objective ranking of candidates awaiting liver transplantation, the process of MELD exception point granting has resulted in inequitable and undesirable outcomes.

More specifically, the MELD exception points policy has disadvantaged women. “Data shows that women have historically had less access to liver transplantation and have had higher death rates on the wait list,” notes Trichakis. “This is due to the awarding of exception points to cancer patients, as more than 75% of those patients are men. Women also tend to have lower muscle mass and higher sodium levels, which lowers their MELD scores.”

Using a state-of-the-art machine learning method developed at the MIT Operations Research Center and real historical data from liver patients, the researchers sought a better way to prioritize the allocation of organs. With OPOM, they asked the question: What is the probability that a patient will either die or become unsuitable for liver transplantation within three months, given his or her individual characteristics?

They found that the OPOM allocation outperformed the MELD-based prediction method in terms of accuracy and fairness. In simulations, OPOM averted significantly more waitlist deaths and removed the bias against women. As a result, it allowed for more equitable and efficient allocation of liver transplants.

“Unlike MELD, which relies on an inexact approach of exception point assignment, OPOM allows for accurate prioritization of all candidates and removes bias for or against particular groups,” says Trichakis.

Bertsimas adds, “If we use this model to change how we measure mortality and allocate livers, the death rate will decrease by 20%, which is very significant. We’re hopeful that our findings will affect the national policy.”

Bertsimas and Trichakis are coauthors of “Development and validation of an Optimized Prediction of Mortality (OPOM) for candidates awaiting liver transplantation” with transplant surgeons Dr. Ryutaro Hirose of the University of California and Dr. Parsia A. Vagefi of the University of Southwestern Medical Center. Additional coauthors include MIT Sloan students Yuchen Wang and Jerry Kung. Their paper has appeared online in the American Journal for Transplantation.

Boost Your Metabolism to Speed Up Weight Loss

ILana Muhlstein, MS, RDN

Metabolism is essentially the rate in which we burn food for energy. Therefore, a slow metabolism doesn’t burn the calories from food as quickly and the excess of calories consumed will be quicker to store as fat. On the upside, someone with a slow metabolism will likely feel more full and energized from less calories and should therefor focus on filling and satisfying low calorie foods.

Cruciferous veggies like Brussels sprouts, broccoli, kale, cauliflower, bok choy, and cabbage are a great example. They are very high in fiber, which can help absorb excess fat and calories and promote elimination. These vegetables also contain iron and calcium, which and both minerals are essential for a healthy working metabolism.

Whey protein, found in protein shake powders like shakeology, are also great for boosting metabolism. Protein requires extra energy to breakdown, causing your body to burn excess calories and jolt your fat burning potential. The lean protein can also stimulate our satiety hormones and contribute to feeling full and satisfied which can prevent overeating. Whey protein also contains leucine, an amino acid, that can help build muscle, which can improve our metabolic rate, aka speed in which we burn calories.

Beans and legumes, like lentils, are amazing for boosting metabolism. They are very rich in plant based protein and iron, both essential for maintaining a healthy metabolism. Additionally, beans and legumes are rich sources of resistant starch. This starch is harder for the body to break down, meaning that it helps keep us fuller longer, can lower our blood sugar response, and encourage our body to burn more calories to break it down. The high fiber content can also help reduce fat storage in the body and improve elimination, which is very helpful for enhancing a positive metabolic system. 

 It has been studied and shown that your metabolism works about 2x stronger in the first half of the day, compared to the second half. You are eating food at the same time that you are engaged in your daily activities which is ideal for burning more calories. Even walking to and from the bathroom, or getting in and out of the car is more calorie-burning than sitting on a couch. In fact, using your brain and reading emails has been shown to burn more calories than watching TV. Therefore, the more you eat in the first half of the day, and the less you eat later at night, the better your metabolism will work.