Posts tagged with "cure"

Cure for Cancer in Israel

Cancer Researchers in Israel Believe They Will Have A Cure For Cancer In 1 Year

Promising Research with Multi-Agent Toxins

According to the WHO/International Agency for Research on Cancer, 18.1 million cancer cases are diagnosed worldwide each year. Cancer is now the second leading cause of death behind cardiovascular diseases. It is imperative now, more than ever, that we continue to seek new methods to treat this devastating illness.

Recently, Accelerated Evolution Biotechnologies did an interview where stated they believe that they will “offer in a year’s time a complete cure for cancer”. Although it grabs headlines, that is a momentous statement to make. Let’s dig a little deeper into the work that they are currently doing. The premise behind their treatment involves using a multi-agent target toxin treatment to treat cancer. In the past, this type of therapy targeted toxin treatment has involved the introduction of DNA coding for a protein (can be an antibody) into a bacteriophage – which is a virus that infects bacteria. These proteins can then be displayed on the surface of the virus and interact with its surroundings.
The company’s therapy involves a similar phenomenon, but with the use of peptides instead of proteins. Peptides consist of two or more amino acids linked together in a chain. They are smaller than proteins, can serve biological functions, and in many ways are less expensive to reproduce.

Most cancer therapies aim at attacking a target in a cell, on the surface of a particular cell, or in one of its internal pathways.

However, a mutation in one of these targets can make the therapy ineffective. What is being done here, with multi-target toxin therapy, is that several peptides of the cancer cell are being targeted with a peptide toxin to avoid mutations rendering a therapy ineffective. The more targets used, the less likely that a series of mutations will occur simultaneously that will make the therapy ineffective. This will help in not allowing the cancer cell to evade the treatment and continue to replicate, even with some mutations occurring.

This may have the ability to reduce side effects as well, given that the peptides will aim to attack specific targets on the cancer cells that are typically not overexpressed in other healthy cells. In addition, since the peptides are small (the ones they have developed are about 12 amino acids long) and lack a rigid structure, it allows them access to regions of the cell that may be blocked if a larger protein was used.

Overall, they are using a “combination modality” in a very specific manner for an attack of each cancer cell in this therapy. Combinational therapy has been successful before with cancer, HIV, and autoimmune disease among others. The goal of the company is to eventually personalize this to each patient by having a biopsy sent and analyzed for the receptors that it over expresses. The patient would then be administered an individualized concoction developed to treat the disease.

This is exciting and has potential, but more data needs to be presented. Thus far they have concluded mice experimentation and found inhibited human cancer cell growth that did not affect healthy mice cells. They are currently working on beginning a round of clinical trials, which many people will be eager to see the conclusions. Recently, Accelerated Evolution Biotechnologies has been writing patents on a variety of different specific peptides. While their work thus far is enthusing and making headlines, their claim to “offer in a year’s time a complete cure for cancer” is likely premature. Yet, I don’t know a single person, including myself, who wouldn’t hope for that.

Joshua Mansour, M.D. is a board-certified hematologist and oncologist in Stanford, California.  He is currently doing additional work in the field of Hematopoietic Stem Cell Transplantation and Cellular Immunotherapy.

WOODBURY COMMON AGAINST BREAST CANCER

Woodbury Common Premium Outlets announced its Spring 2018 More Than Pink movement in support of Susan G. Komen and the fight against breast cancer. As part of its pledge to donate at least $1 million each year in 2017 and 2018, more than 170 participating Simon Malls®, The Mills® and Premium Outlets® nationwide will once again be participating in a range of fundraising activities during the months of April and May.

 

“We are thrilled to launch our Spring 2018 More Than Pink initiatives and have been overwhelmed by the ongoing positive support this movement has garnered with our shoppers, retailers and employees to support Susan G. Komen in its tireless efforts to reduce breast cancer deaths,” said Enna Allen, Simon’s Vice President of Brand Management.

 

From April 14 to May 20, visitors to Woodbury Common Premium Outlets will be able to participate in several programs to help support Susan G. Komen.

 

Discount Card Program: In exchange for a $10 donation to Susan G. Komen, shoppers will receive a Discount Pass, available at Guest Services, providing 25 percent off one item at participating retailers. More than 100 retailers are taking part in the program, including Diane Von Furstenberg, Adidas, Furla, Dooney & Bourke, Kate Spade, La Perla, Lladro, Maje Paris, Pinko, Theory and Vineyard Vines.

 

All Discount Pass donations go to Susan G. Komen.

 

Race for the Cure®: Race for The Cure® events will take place across the U.S. with local Simon teams participating to support the local Susan G. Komen Affiliates. Simon encourages shoppers to join in by locating and registering for an event near them. Woodbury Common Premium Outlets shoppers can join the Komen North Jersey Race For The Cure to be held on Sunday, May 6, in Jersey City, New Jersey. To register go to https://ww5.komen.org/raceforthecure/

 

About Woodbury Common Premium Outlets

Conveniently accessed from New York City via the New York State Thruway at Exit 16, Woodbury Common Premium Outlets features 240 stores including Tory Burch, Celine, Nike, Bottega Veneta, Polo Ralph Lauren, Michael Kors, Burberry, Coach, The North Face, and more, all at a savings of 25 percent to 65 percent every day. Market Hall offers a variety of dining opportunities including Chipotle, Pret A Manger, Pinkberry and more.  To learn more, visit http://www.premiumoutlets.com/outlet/woodbury-common.

About Simon

Simon is a global leader in the ownership of premier shopping, dining, entertainment and mixed-use destinations and an S&P 100 company (Simon Property Group, NYSE:SPG). Our properties across North America, Europe and Asia provide community gathering places for millions of people every day and generate billions in annual sales. For more information, visit simon.com.

 

About Susan G. Komen®

Susan G. Komen is the world’s largest breast cancer organization, funding more breast cancer research than any other nonprofit outside of the federal government while providing real-time help to those facing the disease. Komen has set a Bold Goal to reduce the current number of breast cancer deaths by 50 percent in the U.S. by 2026. Since its founding in 1982, Komen has funded more than $956 million in research and provided more than $2.1 billion in funding to screening, education, treatment and psychosocial support programs, serving millions of people in 60 countries worldwide. Komen was founded by Nancy G. Brinker, who promised her sister, Susan G. Komen, that she would end the disease that claimed Suzy’s life. That promise has become Komen’s promise to all people facing breast cancer. Visit komen.org or call 1-877 GO KOMEN. Connect with us on social at ww5.komen.org/social.

National AIDS Memorial × Quest Diagnostics 100K Grant 

National AIDS Memorial Receives $100,000 Grant from Quest Diagnostics

Quest Diagnostics employees and executives joined more than 100 community volunteers at the National AIDS Memorial to announce a $100,000 grant to Bolster Community Volunteer WorkdaysQuest Diagnostics employees and executives joined more than 100 community volunteers at the National AIDS Memorial to announce a $100,000 grant to bolster the memorial’s volunteer workday program in 2018.

The Quest Diagnostics grant, one of the largest received by the National AIDS Memorial, will support the memorial’s Community Volunteer Workday program in 2018, help fund new equipment, plants, trees and shrubberies and support maintenance and hardscape improvements. The grant will also help underwrite the National AIDS Memorial World AIDS Day commemoration events on November 30 and December 1.

“We are grateful for the support of Quest Diagnostics, as this grant comes at a critical time in our efforts to tell the story of people who have died from AIDS and ensure their stories are known by future generations,” said John Cunningham, Executive Director, National AIDS Memorial. “The community volunteer workdays are at the heart of our mission and this grant provides important funding to support keeping our 10-acre memorial a beautiful space for healing and remembrance.”

Since 1991, nearly 40,000 volunteers have participated in more than 300 Community Volunteer Workdays at the National Aids Memorial, donating more than 200,000 volunteer hours and planting more than 10,000 trees, plants and shrubs. The sacred ground of the 10-acre, living memorial honors all who have confronted the tragic HIV/AIDS pandemic; those who have died, and those who have shared their struggle, kept the vigils and supported each other during their final hours.

“Quest Diagnostics has been a long-time supporter of the National AIDS Memorial and its mission and we are proud to expand our commitment through this grant,” said Thomas Patrick Plewman, General Manager, IDI/General Health and Wellness, Quest Diagnostics. “The memorial is a special place where people from all around the world come to remember loved ones lost to AIDS, which is why we’re proud to help maintain this national landmark and support the memorial’s community activities.”

Nearly 30 years ago, an original Quest Diagnostics company was the first to develop a test that identified the presence of HIV. As of 2014, an estimated 1.2 million people in the U.S. are living with HIV and less than half have ever been tested for the HIV virus. As a leading provider of diagnostics information services, Quest Diagnostics is dedicated to advancing disease management for the HIV community and raising the standards of care in HIV diagnostics and beyond. Whether a patient is dealing with HIV or another condition, Quest Diagnostics helps collaborate and provide accurate information so patients can make the best decisions for their health and well-being.

About the National AIDS Memorial
: The National AIDS Memorial is a dedicated space in the national landscape where millions of Americans touched directly or indirectly by AIDS can gather to heal, hope, and remember. The National AIDS Memorial, known as “the Grove”, was created twenty-five years ago in San Francisco’s Golden Gate Park at the height of the HIV/AIDS epidemic as a place where those impacted by AIDS could both grieve and begin the process of healing. In 1996, legislation sponsored by U.S. Representative Nancy Pelosi was signed into law by President Bill Clinton that elevated “the Grove” as this nation’s sole federally-designated National AIDS Memorial. Today, nearly 40,000 individuals from around the world have contributed 200,000 volunteer hours to support the National AIDS Memorial and its mission to provide, in perpetuity, a place of remembrance so that the lives of people who died from AIDS are not forgotten and the story is known by future generations. For more information visit www.aidsmemorial.org, follow on Facebook @NationalAIDSMemorial and Twitter @AIDS_Memorial.


(Left to Right) Volunteer Todd Watkins and Ashwini Dumaswala, Sr. Director, Quest Diagnostics join more than one-hundred community volunteers at the National AIDS Memorial for the last Community Volunteer Workday of the year where Quest Diagnostics announced a $100,000 grant to bolster the memorial’s volunteer workday program in 2018. Quest Diagnostics is dedicated to advancing disease management for the HIV community and is a leading provider of diagnostics information services. (Photo credit: Marvin Morris)
 

More than 100 community volunteers at the National AIDS Memorial gatherer for the last workday of 2017. Since 1991, nearly 40,000 volunteers have participated in more than 300 Community Volunteer Workdays at the National Aids Memorial, donating more than 200,000 volunteer hours and planting more than 10,000 trees, plants and shrubs. The sacred ground of the 10-acre, living memorial honors all who have confronted the tragic HIV/AIDS pandemic; those who have died, and those who have shared their struggle, kept the vigils and supported each other during their final hours. (Photo credit: Marvin Morris)
  


Quest Diagnostics employees and executives joined more than 100 community volunteers at the National AIDS Memorial during the last Community Volunteer Workday of 2017 to announce a $100,000 grant to bolster the memorial’s volunteer workday program in 2018. The grant from Quest Diagnostics will support the memorial’s Community Volunteer Workday program in 2018 and help fund new equipment, plants, trees and shrubberies and support maintenance and hardscape improvements. events. (Photo credit: Marvin Morris)