Posts tagged with "chronic disease"

The Couch Potato Gene

Regular physical activity is a crucial part of living a healthy lifestyle. However, a majority of American adults spend their waking hours sitting, which leads to a variety of health issues such as obesity, cardiovascular disease and cancer.

Now, a researcher from the University of Missouri has identified a specific gene related to physical inactivity in rats that could potentially play a role in sedentary behavior in humans as well.

“Previous research has shown us that genes play some role in physical inactivity,” said Frank Booth, a professor in the MU College of Veterinary Medicine. “As inactivity leads to chronic disease, we wanted to identify which genes were involved and discovered one in particular, the Protein Kinase Inhibitor Alpha gene, that played a significant role.”

In 2009, Booth took 80 male rats and bred them with 80 female rats. He then placed the rats in voluntary running wheels, similar to those sold in pet stores, and tracked which rats ran the most and least. Over the past decade, Booth selectively bred the highly active rats with each other as well as the “lazy” rats with each other to determine if there is a difference in their genetic makeup. Booth found that the Protein Kinase Inhibitor Alpha gene was significantly less present in the “lazy” rats.

“What makes gene therapy difficult is that most chronic diseases are not caused by just one gene,” Booth said. “For example, there are more than 150 gene variations involved in type 2 diabetes. However, this study is paving the way for future research to identify other genes that might be involved in physical inactivity in humans as well.”

According to government data, costs associated with physical inactivity total $138 billion and account for more than 11% of total health care expenditures. In addition to the financial benefits of a more physically active society, Booth says a better understanding of genetic makeup could help public health officials see physical inactivity as a crucial priority to address.

“Physical inactivity contributes to more than 40 chronic diseases,” Booth said. “Rather than focusing on ways to treat chronic diseases after they have already developed, understanding the contributing factors to physical inactivity could help prevent those chronic diseases from occurring in the first place.”

UFC × Trifecta

UFC®, the world’s premier mixed martial arts organization, today announced a new, multi-year marketing partnership with Trifecta Nutrition, the nation’s largest all-organic meal delivery service. Under the groundbreaking new agreement, Trifecta becomes UFC’s first-ever “Official Meal Delivery Partner”, creating a brand-new sponsorship category for UFC. In return, Trifecta will have a branded presence at the UFC Performance Institute®, the state-of-the-art athlete training facility in Las Vegas, and an activation presence at UFC’s live events. UFC and Trifecta will also collaborate on a co-branded video series and social media campaigns, and Trifecta will utilize UFC branding to create custom delivery boxes and to promote national sweepstakes for UFC events.

“We’re excited to bring Trifecta on board to create a new partnership category for UFC,” said Paul Asencio, UFC Senior Vice President, Global Partnerships. “Meal delivery is a rapidly growing market, and the quality meals and industry leading service Trifecta provides can benefit both fitness-conscious athletes and everyday consumers.”

“UFC is the ideal partner to help us evangelize clean eating and further spread the word about the weight management advantages of healthy meal prep and meal delivery with Trifecta,” said Greg Connolly, Trifecta Co-Founder & CEO. “We have the opportunity to showcase our true value to the fans of UFC with some of the exciting programs we are rolling out together in the coming months.”

UFC and Trifecta first collaborated in November 2017 for UFC® 217: BISPING vs. ST-PIERRE at Madison Square Garden, where the companies unveiled a co-branded training and nutrition video featuring former UFC bantamweight champion Cody Garbrandt. Garbrandt, one of Trifecta’s brand ambassadors, will next face UFC bantamweight champion TJ Dillashaw in a rematch for the UFC bantamweight title in the main event of UFC® 227: DILLASHAW vs. GARBRANDT 2, live on Saturday, August 4, from STAPLES Center in Los Angeles.

In addition to Garbrandt, Trifecta boasts an impressive roster of athletes and celebrities such as “Fittest Man on Earth” Rich Froning, actor Liam Hemsworth, Wonder Woman/Justice League actor and CrossFit star Brooke Ence, and Detroit Lions tight end Luke Willson, along with more than 130 additional NFL players, celebrities and celebrity athletes.

About UFC®

UFC® is a premium global sports brand and the largest Pay-Per-View event provider in the world. Celebrating its 25thAnniversary in 2018, UFC boasts more than 284 million fans worldwide and has produced over 440 events in 22 countries since its inception in 1993. Acquired in 2016 by global sports, entertainment and fashion leader Endeavor (formerly WME | IMG), together with strategic partners Silver Lake Partners and KKR, UFC is headquartered in Las Vegas with a network of employees around the world. UFC produces more than 40 live events annually that consistently sell out some of the most prestigious arenas around the globe, while programming is broadcast in over 160 countries and territories to 1.1 billion TV households worldwide in 40 different languages. UFC FIGHT PASS®, a digital subscription service, delivers exclusive live events, thousands of fights on-demand and original content to fans around the world. For more information, visit UFC.com and follow UFC at Facebook.com/UFC, Twitter, Snapchat and Instagram: @UFC.

About Trifecta

Trifecta is the nation’s largest all-organic meal delivery service founded with a bold mission – to get America back into shape. Eliminating shopping, cooking and cleaning by delivering fully cooked meals directly to customers’ doors in all 50 states, Trifecta’s food is the highest quality in the industry and uses 100% USDA Organic, Gluten, Dairy and Soy-Free ingredients that are never frozen, and Wild Caught/Grass Fed. All their food arrives in a refrigerated case, vacuum sealed and ready to eat. Trifecta offers meals in four categories to meet everyone’s needs including Paleo, Vegan, Clean Eating and Classic Meal and an A La Carte section that operates more like an online grocery store deli. Trifecta is a Title Sponsor of Team USA Weightlifting and the CrossFit Games, teaming up with CrossFit, Inc. to combat chronic disease. Their app “Trifecta – Fitness, Nutrition and Tracking” is the first time an all-in-one solution for people track their food and performance right from their smartphones utilizing Trifecta’s food database 5+ million food items. For more information on Trifecta, visit trifectanutrition.com, download their nutrition app at www.trifectanutrition.com/app and follow them at facebook.com/trifecta meals, @trifectasystem on Instagram and Twitter, or subscribe to them on YouTube at Trifecta.